Metabolomics and Lipidomics performed by SMC in the S3WP Program

scapis articleSwedish Metabolomics Centre has been a collaborating partner in the Swedish SciLifeLab SCAPIS Wellness Profiling (S3WP) program. Read the article on Nature Communcations by following the link below.

Tebani, A., Gummesson, A., Zhong, W. et al. Integration of molecular profiles in a longitudinal wellness profiling cohort. Nat Commun 11, 4487 (2020).

Multiple Tissues Metabolic Profiling of Type 2 Diabetes

Klev Diamanti and his co-workers performed metabolic screening in five key metabolic tissues from 43 multi-organ donors to study metabolic interplay between organs in the development of T2D. The metabolic profiling was performed at Swedish Metabolomics Centre.

figure 1

See the article here:

Diamanti et al. Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes. Sci Rep. 2019;9(1):9653.

Vice Platform Director Anders Nordström Awarded for Research in Metabolomics

Anders Nordstrom 190312 thomaskieselbach 2

Photo: Thomas Kieselbach, Umeå University

Anders Nordström, Vice Platform Director for SMC, has been awarded the Berzelius award by the Swedish Mass Spectrometry Society (SMSS) at the annual symposium March 12th 2019, for his contribution towards developing modern metabolomics. We want to congratulate Anders and wish him good luck with his continued research!

To read more on Kemisamfundets website (in Swedish), click here.

Lipid quantification supports research on diabetic kidney disease

Annelie Falkevall and her co-workers showed that modulating the signalling pathway that controls lipid accumulation in the kidneys might be a possible strategy to treat diabetic kidney disease. Quantification of specific lipids by lipidomics analyses done at the Swedish Metabolomics Centre supported their studies.   
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See the article here:

Falkevall et al., Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease, Cell Metabolism, Volume 25, Issue 3, 7 March 2017, Pages 713-726, ISSN 1550-4131

Do you need help developing an analytical method to answer your biological question?

Aiming to offer new quantitative methods at SMC, we welcome you to send us your targeted method development projects. We can provide pilot scale method development with the purpose of quantifying metabolites of interest for your biological question. Contact the Head of Facility, Annika Johansson, for more information or read the article found under "Method development".

Summary from Swedish Metabolomics Centre, 2013 - 2016 March

Since 2013, we have received more than 211 requests to SMC's service platform. Out of these requests, 150 projects were accepted and 76% have been completed. The accepted projects originated from 101 different researchers, covering 13 of the major institutes of higher education in Sweden. 12 projects were from international customers and 3 from commercial companies.

In the accepted service projects, we have run 14 500 samples from a variety of biological matrices and performed in total 25 000 analyses. We currently have 40 active Open Access users, and 43 000 analyzes have been performed in our Open Access service. 

 Distribution of accepted projects
Distribution of services provided by SMC

Agilent Qual Introduction Workshop - How to evaluate the quality of measurements

Welcome to a workshop for new users of Masshunter Qual. The workshop will cover basic functions in Qual, with a focus on evaluation of the quality of measurements in small to intermediate sample series, using internal standards and endogenous molecules.

Sign up for the workshop by sending an email to This email address is being protected from spambots. You need JavaScript enabled to view it. no later than Monday the 25th of January.

When: Thursday the 28th of January, 09.00 - 15.00
Where: N260

SMC will become a SciLifeLab satellite facility

We are happy to announce that the Board of the Science for Life Laboratory (SciLifeLab) has decided that from year 2016 Swedish Metabolomics Centre will become a SciLifeLab satellite facility.

Waters Seminar about SFC and UPC2 in Umeå, May 19 2015

Waters is hosting a seminar where you can learn about Supercritical Fluid Chromatography developments, as well as learn about within which application areas it is having a significant impact.

Date: Tuesday May 19, 2015
Time: 9.00 - 11.00
Location: KBC, room KBF30

Read more here.

Advanced mass spectrometer to the Swedish Metabolomics Centre

Agilent Technologies, specialists in liquid chromatography and mass spectrometry, promote research at the Swedish Metabolomics Centre in Umeå. During a whole year researchers will be permitted to test run one of the company’s most advanced instruments.

At a seminar at the Chemical Biological Centre in Umeå on September 4th Peter Abrahamsson, Agilent’s product specialist for mass spectrometry in the Nordic countries, had good news: From October Swedish research will have access to their latest technology in mass spectrometry, an Ion Mobility Q-TOF, which will make it possible to conduct metabolite research which currently is difficult to perform anywhere else in Europe.

Watch the video of the announcemen here.